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1

Immunotherapy for gynaecological malignancies

Coukos, George, Conejo-Garcia, Jose R, Roden, Richard BS, Wu, T-C

Journal:

Expert Opinion on Biological Therapy

Year:

2005

Language:

english

File:

PDF, 588 KB

english, 2005

2

Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

Bitler, Benjamin G, Aird, Katherine M, Garipov, Azat, Li, Hua, Amatangelo, Michael, Kossenkov, Andrew V, Schultz, David C, Liu, Qin, Shih, Ie-Ming, Conejo-Garcia, Jose R, Speicher, David W, Zhang, Rug

Journal:

Nature Medicine

Year:

2015

Language:

english

File:

PDF, 2.23 MB

english, 2015

3

Tumor-Infiltrating Dendritic Cell Precursors Recruited by a β-Defensin Contribute to Vasculogenesis under the Influence of VEGF-A in Ovarian Cancer

Conejo-Garcia, Jose-Ramon, Benencia, Fabian, Coukos, George

Journal:

Journal of Immunotherapy

Year:

2004

Language:

english

File:

PDF, 829 KB

english, 2004

4

Antitumoral activity of 1,2-diaminocyclohexane derivatives in breast, colon and skin human cancer cells

Morales, Fátima, Ramírez, Alberto, Morata-Tarifa, Cynthia, Navarro, Saúl A, Marchal, Juan A, Campos, Joaquín M, Conejo-García, Ana

Journal:

Future Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.08 MB

english, 2017

5

IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment

Perales-Puchalt, Alfredo, Svoronos, Nikolaos, Villarreal, Daniel O., Zankharia, Urvi, Reuschel, Emma, Wojtak, Krzysztof, Payne, Kyle K., Duperret, Elizabeth K., Muthumani, Kar, Conejo-Garcia, Jose R.,

Journal:

Year:

2019

Language:

english

File:

PDF, 2.19 MB

english, 2019

6

Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer

Annapragada, Ananth, Sikora, Andrew, Bollard, Catherine, Conejo-Garcia, Jose, Cruz, Conrad Russell, Demehri, Shadmehr, Demetriou, Michael, Demirdjian, Levon, Fong, Lawrence, Horowitz, Mary, Hutson, Al

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2020

File:

PDF, 3.35 MB

2020

7

Choline Kinase Inhibitory Effect and Antiproliferative Activity of New 1,1′,1′′-(Benzene-1,3,5-triylmethylene)tris{4- [(disubstituted)amino]pyridinium} Tribromides.

Ana Conejo-Garcia, Joaquin Campos, Rosario M. Sanchez, Agustin Rodriguez-Gonzalez, Juan C. Lacal, Miguel A. Gallo, Antonio Espinosa

Journal:

Year:

2003

File:

PDF, 113 KB

2003

8

A Prodrug System for Hydroxylamines Based on Esterase Catalysis.

Ana Conejo-Garcia, Christopher J. Schofield

Journal:

Year:

2005

File:

PDF, 16 KB

2005

9

ChemInform Abstract: Synthesis of Purine Derivatives as Scaffolds for a Diversity of Biological Activities

A. Conejo-Garcia, O. Cruz-Lopez, V. Gomez-Perez, F. Morales, M. E. Garcia-Rubino, M. Kimatrai, M. C. Nunez, J. M. Campos

Journal:

Year:

2011

File:

PDF, 18 KB

2011

10

ChemInform Abstract: Syntheses of 2,3-Dihydro-1,4-benzodioxins and Bioisosteres as Structural Motifs for Biologically Active Compounds

Olga Cruz-Lopez, Maria C. Nunez, Ana Conejo-Garcia, Maria Kimatrai, Joaquin M. Campos

Journal:

Year:

2011

File:

PDF, 18 KB

2011

11

ChemInform Abstract: Synthesis and Anticancer Activity of (RS)-9-(2,3-Dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

Ana Conejo-Garcia, M. Eugenia Garcia-Rubino, Juan A. Marchal, M. Carmen Nunez, Alberto Ramirez, Sandro Cimino, M. Angel Garcia, Antonia Aranega, Miguel A. Gallo, Joaquin M. Campos

Journal:

Year:

2012

File:

PDF, 31 KB

2012

12

Synthesis and Anticancer Activity of (R,S)-9-(2,3-Dihydro-1,4-Benzoxathiin-3-ylmethyl)-9H-Purines

Mónica Díaz-Gavilán, Ana Conejo-García, Olga Cruz-López, María C. Núñez, Duane Choquesillo-Lazarte, Josefa M. González-Pérez, Fernando Rodríguez-Serrano, Juan A. Marchal, Antonia Aránega, Miguel A. Ga

Journal:

Year:

2008

Language:

english

File:

PDF, 367 KB

english, 2008

13

Synthesis and Anticancer Activity of the (R,S)-Benzofused 1,5-Oxathiepine Moiety Tethered to Purines through Alkylidenoxy Linkers

Dr. María Kimatrai, Prof. Ana Conejo-García, Alberto Ramírez, Elena Andreolli, Dr. Adriane Da Silveira-Gomes, Dr. María Angel García, Prof. Antonia Aránega, Prof. Juan A. Marchal, Prof. Joaquín M. Cam

Journal:

Year:

2011

Language:

english

File:

PDF, 370 KB

english, 2011

14

1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives

Joaquín M. Campos, Rosario M. Sánchez-Martín, Olga Cruz-López, Ana Conejo-García, Miguel A. Gallo, Antonio Espinosa

Journal:

Magnetic Resonance in Chemistry

Year:

2005

Language:

english

File:

PDF, 106 KB

english, 2005

15

Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor

Ana Conejo-Garcia, Michael A. McDonough, Christoph Loenarz, Luke A. McNeill, Kirsty S. Hewitson, Wei Ge, Benoît M. Liénard, Christopher J. Schofield, Ian J. Clifton

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 602 KB

english, 2010

16

Towards a model for the inhibition of choline kinase by a new type of inhibitor

Ana Conejo-García, Antonio Entrena, Joaquín M. Campos, Rosario M. Sánchez-Martín, Miguel A. Gallo, Antonio Espinosa

Journal:

European Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 260 KB

english, 2005

17

Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines

Ana Conejo-García, María C. Núñez, Juan A. Marchal, Fernando Rodríguez-Serrano, Antonia Aránega, Miguel A. Gallo, Antonio Espinosa, Joaquín M. Campos

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 237 KB

english, 2008

18

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine

Luisa C. López-Cara, Ana Conejo-García, Juan A. Marchal, Giuseppe Macchione, Olga Cruz-López, Houria Boulaiz, María A. García, Fernando Rodríguez-Serrano, Alberto Ramírez, Carlos Cativiela, Ana I. Jim

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 642 KB

english, 2011

19

A prodrug system for hydroxylamines based on esterase catalysis

Ana Conejo-Garcia, Christopher J. Schofield

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 684 KB

english, 2005

20

ORIGINAL ARTICLE: Human Uterine NK Cells Interact with Uterine Macrophages via NKG2D upon Stimulation with PAMPs

Satarupa Basu, Mikael Eriksson, Patricia A. Pioli, Jose Conejo-Garcia, Teddy F. Mselle, Satoshi Yamamoto, Charles R. Wira, Charles L. Sentman

Journal:

American Journal of Reproductive Immunology

Year:

2009

Language:

english

File:

PDF, 389 KB

english, 2009

21

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Curiel, Tyler J, Coukos, George, Zou, Linhua, Alvarez, Xavier, Cheng, Pui, Mottram, Peter, Evdemon-Hogan, Melina, Conejo-Garcia, Jose R, Zhang, Lin, Burow, Matthew

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 741 KB

english, 2004

22

Tumor-infiltrating dendritic cell precursors recruited by a β-defensin contribute to vasculogenesis under the influence of Vegf-A

Conejo-Garcia, Jose R, Benencia, Fabian, Courreges, Maria-Cecilia, Kang, Eugene, Mohamed-Hadley, Alisha, Buckanovich, Ronald J, Holtz, David O, Jenkins, Ann, Na, Hana, Zhang, Lin

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 1.41 MB

english, 2004

23

The role of dendritic cell precursors in tumour vasculogenesis

Coukos, G, Benencia, F, Buckanovich, R J, Conejo-Garcia, J R

Journal:

British Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

24

Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efficacy of dendritic cell vaccines

Courrèges, M C, Benencia, F, Conejo-García, J R, Zhang, L, Coukos, G

Journal:

Cancer Gene Therapy

Year:

2005

Language:

english

File:

PDF, 413 KB

english, 2005

25

Structure determination of human and murine β-defensins reveals structural conservation in the absence of significant sequence similarity

Finn Bauer, Kristian Schweimer, Enno Klüver, Jose-Ramon Conejo-Garcia, Wolf-Georg Forssmann, Paul Rösch, Knut Adermann, Heinrich Sticht

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 310 KB

english, 2001

26

Nanomolecular targeting of dendritic cells for ovarian cancer therapy

Cubillos-Ruiz, Juan R, Fiering, Steven, Conejo-Garcia, Jose R

Journal:

Future Oncology

Year:

2009

Language:

english

File:

PDF, 870 KB

english, 2009

27

1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety

Belén Rubio-Ruiz, Ana Conejo-García, Miguel A. Gallo, Antonio Espinosa, Antonio Entrena

Journal:

Magnetic Resonance in Chemistry

Year:

2012

Language:

english

File:

PDF, 128 KB

english, 2012

28

Mesothelin, a novel immunotherapy target for triple negative breast cancer

Julia Tchou, Liang-Chuan Wang, Ben Selven, Hongtao Zhang, Jose Conejo-Garcia, Hossein Borghaei, Michael Kalos, Robert H. Vondeheide, Steven M. Albelda, Carl H. June, Paul J. Zhang

Journal:

Breast Cancer Research and Treatment

Year:

2012

Language:

english

File:

PDF, 513 KB

english, 2012

29

Estradiol regulates MICA expression in human endometrial cells

Satarupa Basu, Patricia A. Pioli, Jose Conejo-Garcia, Charles R. Wira, Charles L. Sentman

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 1008 KB

english, 2008

30

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines

Ana Conejo-García, M. Eugenia García-Rubiño, Juan A. Marchal, M. Carmen Núñez, Alberto Ramírez, Sandro Cimino, M. Ángel García, Antonia Aránega, Miguel A. Gallo, Joaquín M. Campos

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 397 KB

english, 2011

31

Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors

Belén Rubio-Ruíz, Ana Conejo-García, Pablo Ríos-Marco, María Paz Carrasco-Jiménez, Josefa Segovia, Carmen Marco, Miguel A. Gallo, Antonio Espinosa, Antonio Entrena

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 828 KB

english, 2012

32

The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis

Octavio Caba, Fernando Rodríguez-Serrano, Mónica Díaz-Gavilán, Ana Conejo-García, Raúl Ortiz, Antonio Martínez-Amat, Pablo Álvarez, Miguel A. Gallo, Joaquín M. Campos, Juan A. Marchal, Antonia Aránega

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 358 KB

english, 2012

33

Phagocytes mediate targeting of iron oxide nanoparticles to tumors for cancer therapy

Toraya-Brown, Seiko, Sheen, Mee Rie, Baird, Jason R., Barry, Stephen, Demidenko, Eugene, Turk, Mary Jo, Hoopes, P. Jack, Conejo-Garcia, Jose R., Fiering, Steven

Journal:

Integrative Biology

Year:

2013

Language:

english

File:

PDF, 3.42 MB

english, 2013

34

Different Effects of Glucose Starvation on Expression and Stability of VEGF mRNA Isoforms in Murine Ovarian Cancer Cells

Lin Zhang, Jose-Ramon Conejo-Garcia, Nuo Yang, Wei Huang, Alisha Mohamed-Hadley, Weijia Yao, Fabian Benencia, George Coukos

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 322 KB

english, 2002

35

Distribution of new human β-defensin genes clustered on chromosome 20 in functionally different segments of epididymis

Francisco-Javier Rodríguez-Jiménez, Alexander Krause, Sandra Schulz, Wolf-Georg Forssmann, José-Ramón Conejo-Garcia, Rainer Schreeb, Dirk Motzkus

Journal:

Year:

2003

Language:

english

File:

PDF, 737 KB

english, 2003

36

Macrophages infiltrating the tissue in chronic pancreatitis express the chemokine receptor CCR5

Helmuth Goecke, Ulf Forssmann, Mariagrazia Uguccioni, Helmut Friess, Jose R. Conejo-Garcia, Arthur Zimmermann, Marco Baggiolini, Markus W. Büchler

Journal:

Year:

2000

Language:

english

File:

PDF, 1.07 MB

english, 2000

37

Mast cells impair the development of protective anti-tumor immunity

Anna Wasiuk, Dyana K. Dalton, William L. Schpero, Radu V. Stan, Jose R. Conejo-Garcia, Randolph J. Noelle

Journal:

Cancer Immunology, Immunotherapy

Year:

2012

Language:

english

File:

PDF, 596 KB

english, 2012

38

Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer

Heather L Pulaski, Gregory Spahlinger, Ines A Silva, Karen McLean, Angela S Kueck, R Kevin Reynolds, George Coukos, Jose R Conejo-Garcia, Ronald J Buckanovich

Journal:

Journal of Translational Medicine

Year:

2009

Language:

english

File:

PDF, 2.06 MB

english, 2009

39

Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma

Deng, Z., Wang, Z., Xiang, C., Molczan, A., Baubet, V., Conejo-Garcia, J., Xu, X., Lieberman, P. M., Dahmane, N.

Journal:

Journal of Cell Science

Year:

2012

Language:

english

File:

PDF, 6.47 MB

english, 2012

40

The Mechanism of Allosteric Coupling in Choline Kinase α1 Revealed by the Action of a Rationally Designed Inhibitor

Sahún-Roncero, María, Rubio-Ruiz, Belén, Saladino, Giorgio, Conejo-García, Ana, Espinosa, Antonio, Velázquez-Campoy, Adrián, Gervasio, Francesco Luigi, Entrena, Antonio, Hurtado-Guerrero, Ramon

Journal:

Angewandte Chemie International Edition

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

41

Isolation and biochemical characterization of LEAP-2, a novel blood peptide expressed in the liver

Alexander Krause, Rannar Sillard, Burkhard Kleemeier, Enno Klüver, Erik Maronde, José Ramon Conejo-García, Wolf Georg Forssmann, Peter Schulz-Knappe, Michael C. Nehls, Frank Wattler, Sigrid Wattler, K

Journal:

Protein Science

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

42

Anti-tumor immunity: Myeloid leukocytes control the immune landscape

Rutkowski, Melanie R., Stephen, Tom L., Conejo-Garcia, Jose R.

Journal:

Cellular Immunology

Year:

2012

Language:

english

File:

PDF, 328 KB

english, 2012

43

The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by β-oxocarboxylic acids

Banerji, Biswadip, Conejo-Garcia, Ana, McNeill, Luke A., McDonough, Michael A., Buck, Matthew R. G., Hewitson, Kirsty S., Oldham, Neil J., Schofield, Christopher J.

Journal:

Chemical Communications

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

44

Influence of the Linker in Bispyridium Compounds on the Inhibition of Human Choline Kinase

Conejo-García, Ana, Báñez-Coronel, Mónica, Sánchez-Martín, Rosario M., Rodríguez-González, Agustín, Ramos, Angeles, Ramírez de Molina, Ana, Espinosa, Antonio, Gallo, Miguel Angel, Campos, Joaquín M.,

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

45

Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

Zhang, Lin, Conejo-Garcia, Jose R., Katsaros, Dionyssios, Gimotty, Phyllis A., Massobrio, Marco, Regnani, Giorgia, Makrigiannakis, Antonis, Gray, Heidi, Schlienger, Katia, Liebman, Michael N., Rubin,

Journal:

Boston Medical and Surgical Journal

Year:

2003

Language:

english

File:

PDF, 350 KB

english, 2003

46

Antiproliferative Activity, Cell Cycle, and Apoptosis Studies of a Series of 6-Substituted 9 H -Purin-9-yl-pyridinium Derivatives on a Human Cervical Carcinoma Cell Line

Rubio-Ruiz, Belén, Ramos-Torrecillas, Javier, Capitán-Cañadas, Fermín, Sánchez-Martín, Rosario, Gallo, Miguel Ángel, Espinosa, Antonio, Ruiz, Concepción, Conejo-García, Ana, Entrena, Antonio

Journal:

Year:

2013

Language:

english

File:

PDF, 505 KB

english, 2013

47

Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition

Amatangelo, Michael, Garipov, Azat, Li, Hua, Conejo-Garcia, Jose R., Speicher, David, Zhang, Rugang

Journal:

Year:

2013

Language:

english

File:

PDF, 1.78 MB

english, 2013

48

Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer

Tchou, Julia, Zhang, Paul J., Bi, Yingtao, Satija, Celine, Marjumdar, Rajrupa, Stephen, Tom L., Lo, Albert, Chen, Haiying, Mies, Carolyn, June, Carl H., Conejo-Garcia, Jose, Puré, Ellen

Journal:

Human Pathology

Year:

2013

Language:

english

File:

PDF, 2.22 MB

english, 2013

49

A role for the chemokine receptor CCR6 in mammalian sperm motility and chemotaxis

Caballero-Campo, Pedro, Buffone, Mariano G., Benencia, Fabian, Conejo-García, José R., Rinaudo, Paolo F., Gerton, George L.

Journal:

Journal of Cellular Physiology

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

50

Chromatographic Enantioresolution of Six Purine Derivatives Endowed with Anti-Human Breast Cancer Activity

Natalini, Benedetto, Sardella, Roccaldo, Ianni, Federica, García-Rubiño, María Eugenia, Conejo-García, Ana, Núñez, María del Carmen, Gallo, Miguel Angel, Campos, Joaquín María

Journal:

Chromatographia

Year:

2013

Language:

english

File:

PDF, 287 KB

english, 2013

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